Request for Proposal (RFP): Proteomics data generation services for MLSC Biobank Program

1. Background and Purpose 

MLSC seeks proposals from qualified vendors to perform proteomics analyses on biospecimens collected through the Biobank Program. These services will support discovery, biomarker development, and translational research.   

2. Scope of Work 

A. Sample Preparation 

• Processing of plasma, serum, tissue, or other approved sample types, as well as MA regulations for handling human samples.
• Standardized protocols to minimize variability. 
• Documentation of pre-analytical variables. 

 B. Proteomics Analysis 

• High-throughput, research-grade proteomic profiling. 
• Support for discovery and targeted workflows where applicable. 
• Reproducible and validated analytical pipelines. 

 C. Data Output and QC 

• Delivery of raw and processed proteomics data. 
• Defined quality metrics and performance reporting. 
• Annotation of proteins and analytical parameters. 

D. Data Integration 

• Secure data transfer to MLSC-designated platforms. 
• Alignment with biobank metadata and clinical data. 

 3. Vendor Qualifications 

• Experience with large-scale proteomics studies. 
• Demonstrated reproducibility and analytical rigor. 
• Ability to support multi-site biobank initiatives. 

4. Proposal Requirements  

Executive summary, technical methodology, QC standards, experience, implementation plan, pricing, and assumptions.   

5. Evaluation Criteria   

Analytical rigor, scalability, data quality, integration readiness, experience, and cost.

6. Timeline

Deadline: 4.17.2026

Evaluation Period: Proposals will be weighted based on technical expertise, alignment with the MLSC’s needs and cost-efficiency. Finalists may be interviewed in mid/late May. A decision will be made in May/June with a tentative commencement in June.   

MLSC reserves the right to modify this timeline at its discretion.   

7. Additional Terms 

For questions regarding this RFP, contact: BioBank@masslifesciences.com

This RFP does not constitute an obligation to fund any proposals. The MLSC reserves the right to modify or cancel this RFP at any time and may request further clarifications or conduct interviews as part of the selection process.