Request for Proposal (RFP): Transcriptomics Services for MLSC Biobank Program

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1. Background and Purpose

MLSC is soliciting proposals for transcriptomics services to support gene expression profiling of biospecimens collected through the Biobank Program. These data will be linked with other molecular and clinical data to enable multi-omics research. 

2. Scope of Work

A. Sample Handling 

  • RNA quality assessment and preparation. 
  • Support for tissue and blood-derived samples. 
  • Adherence to standardized handling and storage requirements. 

 B. Transcriptomic Profiling 

  • Bulk or single-cell transcriptomic workflows, as applicable. 
  • Reproducible library preparation and sequencing processes. 
  • Defined quality metrics. 

 C. Data Delivery 

  • Secure delivery of raw and processed transcriptomic data. 
  • QC reports and metadata. 
  • Compatibility with MLSC bioinformatics infrastructure. 

 D. Compliance and Security 

  • Compliance with human subject data protections, as well as MA regulations for handling human samples.
  • Secure handling and transfer of data. 

3. Vendor Qualifications 

  • Experience delivering transcriptomic services at scale. 
  • Strong quality control and documentation practices. 
  • Familiarity with multi-omics integration. 

4. Proposal Requirements

Executive summary, technical approach, QC and validation, experience, implementation timeline, pricing, and assumptions.   

5. Evaluation Criteria 

Technical quality, scalability, integration readiness, experience, and cost.   

6. Timeline 

Deadline: 4.17.2026   

Evaluation Period: Proposals will be weighted based on technical expertise, alignment with the MLSC’s needs and cost-efficiency. Finalists may be interviewed in mid/late May. A decision will be made in May/June with a tentative commencement in June.

MLSC reserves the right to modify this timeline at its discretion.   

7. Additional Terms 

For questions regarding this RFP, contact: BioBank@masslifesciences.com 

This RFP does not constitute an obligation to fund any proposals. The MLSC reserves the right to modify or cancel this RFP at any time and may request further clarifications or conduct interviews as part of the selection process.    

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